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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYBL2
All Species:
12.73
Human Site:
S223
Identified Species:
21.54
UniProt:
P10244
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10244
NP_002457.1
700
78764
S223
Q
P
T
E
G
Q
G
S
L
L
T
N
W
P
S
Chimpanzee
Pan troglodytes
XP_514658
769
86303
S223
Q
P
T
E
G
Q
G
S
L
L
T
N
W
P
S
Rhesus Macaque
Macaca mulatta
XP_001084853
700
78675
S223
Q
P
T
E
G
Q
G
S
L
L
T
N
W
P
S
Dog
Lupus familis
XP_534424
883
97262
S406
R
P
V
E
E
Q
G
S
L
M
T
N
W
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P48972
704
79084
L223
P
V
D
G
Q
G
S
L
V
S
S
W
P
L
V
Rat
Rattus norvegicus
NP_001100006
704
79549
L223
P
V
E
G
P
G
S
L
V
S
S
W
P
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511778
753
85883
P229
T
Q
N
Q
F
Y
I
P
V
Q
I
P
G
Y
Q
Chicken
Gallus gallus
Q03237
686
77718
L201
K
E
S
Q
P
L
Y
L
L
V
E
V
D
D
N
Frog
Xenopus laevis
P52551
743
82891
R223
L
L
S
E
P
V
E
R
S
A
N
I
P
E
E
Zebra Danio
Brachydanio rerio
NP_001003867
633
70853
K182
N
H
W
N
S
T
I
K
R
K
V
E
T
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797351
686
76826
D230
K
I
Y
T
P
D
S
D
F
M
N
A
N
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P20024
340
36221
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7G7
776
86488
G227
M
H
S
N
G
D
E
G
S
S
R
P
G
V
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O13493
324
36522
Conservation
Percent
Protein Identity:
100
88
98.2
72.5
N.A.
85.2
87.7
N.A.
38.3
72.5
54.2
52.1
N.A.
N.A.
N.A.
N.A.
37.8
Protein Similarity:
100
89.7
98.7
74.7
N.A.
89.4
91.3
N.A.
54.5
81.5
69
65.8
N.A.
N.A.
N.A.
N.A.
54
P-Site Identity:
100
100
100
66.6
N.A.
0
0
N.A.
0
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
13.3
20
N.A.
13.3
40
13.3
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
20.1
N.A.
25.5
N.A.
20.7
Protein Similarity:
N.A.
31.8
N.A.
40.8
N.A.
29.5
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
0
N.A.
13.3
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
15
0
8
0
0
0
0
8
8
8
% D
% Glu:
0
8
8
36
8
0
15
0
0
0
8
8
0
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
15
29
15
29
8
0
0
0
0
15
8
0
% G
% His:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
15
0
0
0
8
8
0
0
8
% I
% Lys:
15
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% K
% Leu:
8
8
0
0
0
8
0
22
36
22
0
0
0
15
0
% L
% Met:
8
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
8
0
8
15
0
0
0
0
0
0
15
29
8
0
8
% N
% Pro:
15
29
0
0
29
0
0
8
0
0
0
15
22
29
8
% P
% Gln:
22
8
0
15
8
29
0
0
0
8
0
0
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% R
% Ser:
0
0
22
0
8
0
22
29
15
22
15
0
0
8
22
% S
% Thr:
8
0
22
8
0
8
0
0
0
0
29
0
8
0
0
% T
% Val:
0
15
8
0
0
8
0
0
22
8
8
8
0
8
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
15
29
0
0
% W
% Tyr:
0
0
8
0
0
8
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _